Potential health benefits of CBDA, Humans have used the fibers, food, and medicine characteristics of cannabis for a long time. However, the plant’s chemical composition has only been discovered in the last few decades. There have been numerous cannabinoids discovered in studies dating back to the 1970s. Among these is the well-known intoxicating THC, but there are others.
In addition to cannabinoids, cannabis includes many other useful components, such as polyunsaturated fatty acids, proteins, and terpenes. Scientists and the general public, on the other hand, have focused on cannabinoids. THC and CBD are the two cannabinoids that have been thoroughly studied.
THC is the principal ingredient in marijuana and is responsible for its intoxicating effects of marijuana. Most individuals know CBD’s wide range of health advantages and potential side effects. Then there’s CBDA, which is a lesser-known cannabinoid.
What Is CBDA?
As the name suggests, CBDA is a cannabinoid acid that shares many characteristics with CBD. Decarboxylation of CBDA results in the formation of CBD, making it the “parent molecule” of CBD.
Carbamic acid is the scientific name for CBDA. That indicates that the structure has a carboxyl group, often represented as COOH, containing one carbon, one hydrogen, and two oxygen atoms. When this molecule is heated to a high temperature, it breaks into carbon dioxide and hydrogen, respectively. All that’s left is CBD, the scientific term for the substance.
These reactions do occur more or less naturally over time, but the rate at which they occur is staggering. However, the process is substantially accelerated when cannabis is smoked, heated in a vaporizer, or baked in an oven.
The decarboxylation process is critical if you’ve ever cooked with cannabis. Cannabis’ THC and CBD can be activated and boosted significantly by using this product.
Potential health benefits of CBDA
Compared to its cousins CBD and THC, little research has been done on CBDA. Some positive results have been reported from studies looking at the impact of CBDA on various illnesses.
CBDA as a cancer treatment
Among the illnesses for which CBDA provides hope are breast cancer and other cancers. CBDA has been shown in studies by Takeda et al. to suppress breast cancer cells and prevent them from dispersing throughout the body, called metastasis.
Cyclooxygenase-2 was found to be down regulated in cancer cells after only 48 hours of exposure to CBDA, according to the study’s findings (COX-2). An important factor in the development of invasive breast cancer is inflammation, which this enzyme may cause. As a bonus, CBDA was found to stimulate the expression of the breast cancer metastasis-inhibiting gene SHARP1 (also known as BHLHE41).
Because specialists estimate that up to 90% of breast cancer fatalities are due to metastases, there is a good chance that this discovery about CBDA will help people who have been diagnosed with this potentially fatal ailment.
Anti-Inflammatory Effects of CBDA
CBDA, like the more well-known cannabinoid CBD, appears to inhibit COX-2, making it an anti-inflammatory agent. Inhibiting COX-2 is a common mechanism of action for conventional anti-inflammatory medications.
Doctors frequently prescribe these medications to relieve discomfort caused by diseases like arthritis. CBDA could alleviate joint pain and arthritis symptoms even though no trials have been done.
CBDA for Vomiting and Nausea
So CBDA has been extensively studied for its potential to alleviate symptoms of nausea and vomiting. Toxin and motion-induced vomiting were successfully relieved in shrews by CBDA, according to a study done by Bolognini et al., while lessened nausea in rats. To put it another way, these researchers contend that CBDA may be even more beneficial than CBD in reducing motion sickness and nausea symptoms.
CBDA appears to enhance 5-HT1A receptor activation, resulting in very powerful effects. These receptors are designed to connect with the neurotransmitter serotonin in the digestive system.
It would help if you studied the effects of CBDA on nausea and vomiting in people further. If the cannabinoid is proven effective, it could help alleviate the negative effects of chemotherapy and nausea caused by other medical illnesses.
CBDA is a Psychedelic Supplement
CBDA isolate is being used in this manner, even though there is little evidence to back it up. Nevertheless, this chemical may be beneficial in the treatment of anxiety and stress. When coupled with antipsychotic medication, CBDA and other cannabinoids have been patented by one business.
What is the best way to use CBDA?
The ideal way to ingest CBDA is through tinctures, topical, and balms made from raw hemp flower (CBD). Natural hemp oil is not cooked (decarboxylated) – so all of the naturally occurring CBDA is present in the oil (tincture).
If you don’t like hemp’s taste (cannabis), you can use raw hemp oil in smoothies, juices, and other foods to enhance their nutritional content. CBDA will start converting into CBD if you eat hot meals, so keep that in mind.
The unprocessed form of CBD is known as CBDA. Raw hemp oils, which have a high concentration of CBDA and CBD, are the only way to absorb CBDA because, once cooked, CBDA transforms into CBD.
It’s important to remember that not all full-spectrum CBD oils are raw; some have been heated (to convert the CBDA in the oil to the CBD) or even destroyed (to generate an isolated form of CBD).
Isn’t CBDA high?
No. CBDA has no psychoactive effects. There are just trace levels of THC (the ingredient that makes you feel euphoric) in most raw hemp oils, and that is practically insufficient to provide any psychoactive effects.
Conclusion
With its promise in the medical field and interest in science, CBDA is now being studied in greater depth. We are eager to learn more about the health benefits of CBDA.
For medical purposes, CBDA appears to be a potential phytocannabinoid. Research into CBDA’s full potential is still needed, although you can already use it to treat epilepsy, anxiety and depression, and cancer-related vomiting.
CBDA is also an anti-inflammatory drug. CBDA’s absence of negative effects makes it an excellent choice for long-term use. To reap the benefits of CBDA, you must use raw hemp (CBD) oil!